GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | trans | rs965513 | 1 | rs7030241 | chr9:100550375 | TTC8 | chr14:89290497-89344334:+ | 0.24 | 6 | 3.88E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030256 | chr9:100535203 | ABCC11 | chr16:48200822-48281479:- | 0.3 | 5.93 | 5.87E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030256 | chr9:100535203 | BMPR1A | chr10:88516396-88684944:+ | -0.24 | -6.19 | 1.27E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030256 | chr9:100535203 | CLDN2 | chrX:106143394-106174091:+ | 0.27 | 6.17 | 1.48E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030256 | chr9:100535203 | EFNB2 | chr13:107142098-107187337:- | -0.26 | -6 | 3.84E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030256 | chr9:100535203 | EML5 | chr14:89081205-89259157:- | 0.3 | 6.76 | 4.15E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030256 | chr9:100535203 | EPDR1 | chr7:37960163-37991539:+ | 0.34 | 7.51 | 2.96E-13 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030256 | chr9:100535203 | GGT5 | chr22:24615623-24641110:- | 0.26 | 5.89 | 7.32E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030256 | chr9:100535203 | LRRC42 | chr1:54412037-54433839:+ | -0.23 | -6.05 | 2.96E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030256 | chr9:100535203 | NKX6-1 | chr4:85414436-85419387:- | 0.51 | 8.85 | 1.75E-17 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030280 | chr9:100535267 | ABCC11 | chr16:48200822-48281479:- | 0.3 | 6.04 | 3.02E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030280 | chr9:100535267 | BMPR1A | chr10:88516396-88684944:+ | -0.25 | -6.4 | 3.81E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030280 | chr9:100535267 | CLDN2 | chrX:106143394-106174091:+ | 0.26 | 6.14 | 1.72E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030280 | chr9:100535267 | EFNB2 | chr13:107142098-107187337:- | -0.25 | -5.95 | 5.21E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030280 | chr9:100535267 | EML5 | chr14:89081205-89259157:- | 0.3 | 6.84 | 2.41E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |